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Pharmacology 204 · Lecture 07
SummaryTranscriptCardsQuestions
Overview

Beta-blockers cut cardiac output by blocking β1 receptors in the myocardium. Most of the class went on selectivity — which agents hit β1 only, and why that matters when the patient has asthma.

Key points
  • β2 receptors sit in bronchial smooth muscle — blocking them can trigger bronchospasm.
  • Propranolol is non-selective. Atenolol, metoprolol and bisoprolol are β1-selective.
  • Flagged twice as examinable: the selectivity table.

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